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Chlamydia Basic Research Society biennial meeting in Seattle in March 2019

Members of the Carabeo lab will be giving poster and oral presentations at the upcoming CBRS meeting in Seattle. Postdoctoral fellow, Amanda Brinkworth has been selected to give a talk on her project using fast fluorescent timers to monitor transcriptional activity at select promoters during normal and stressed develoment of Chlamydia trachomatis. Korinn Murphy, a 3rd-year graduate student will present her findings on how Chlamydia trachomatis stabilizes focal adhesions of epithelial cells. 4th-year graduate student, Nick Pokorzynski will give a poster presentation and a lightning talk on how the YtgR transcriptional repressor regulates the transcription of the trp operon at the levels of transcriptional initiation and termination. Liam Caven, a 4th-year graduate student will present a poster describing how Chlamydia overrides the signaling mechanism that keeps the host transcription factor YAP inhibited in high-density growth of epithelial cells. 2nd-year graduate student Matt Romero will present his data that elucidate the functional relationship between two actin nucleators during Chlamydia invasion. Finally, three undergraduate researchers, Terran Galbreath, Deshae McNeil, and Katrina Nielsen will present a poster describing their work with fast fluorescent timers and their utility in monitoring transcriptional activities throughout the chlamydial developmental cycle.

The Carabeo lab receives its second R01 award from the NIH!

This award is a multi-principal investigator R01 with Dr. Lisa Rucks and Dr. Scot Ouellette of the Department of Pathology and Microbiology at the University of Nebraska Medical Center. The grant will support three independent, but related projects with a focus on the REGULATORY ROLE OF TANDEM TRYPTOPHAN CODONS IN CHLAMYDIAL PERSISTENCE.

Nick Pokorzynski receives an F31 Predoctoral Fellowship from the NIH with a perfect score!!!

The two-year fellowship, titled "THE MOLECULAR BASIS FOR INTEGRATION OF THE CHLAMYDIAL RESPONSES TO IRON AND TRYPTOPHAN LIMITATION" will support Nick's thesis project on the regulation of the chlamydial trp operon by both the trp repressor and the iron-dependent YtgR transcriptional regulator.  CONGRATULATIONS, NICHOLAS!

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